diff --git a/runelite-client/src/main/java/net/runelite/client/plugins/lowmemory/LowMemoryPlugin.java b/runelite-client/src/main/java/net/runelite/client/plugins/lowmemory/LowMemoryPlugin.java
index 195feefaf4..66270da3ad 100644
--- a/runelite-client/src/main/java/net/runelite/client/plugins/lowmemory/LowMemoryPlugin.java
+++ b/runelite-client/src/main/java/net/runelite/client/plugins/lowmemory/LowMemoryPlugin.java
@@ -26,7 +26,10 @@ package net.runelite.client.plugins.lowmemory;
 
 import javax.inject.Inject;
 import net.runelite.api.Client;
+import net.runelite.api.GameState;
+import net.runelite.api.events.GameStateChanged;
 import net.runelite.client.callback.ClientThread;
+import net.runelite.client.eventbus.Subscribe;
 import net.runelite.client.plugins.Plugin;
 import net.runelite.client.plugins.PluginDescriptor;
 
@@ -47,7 +50,10 @@ public class LowMemoryPlugin extends Plugin
 	@Override
 	protected void startUp()
 	{
-		clientThread.invoke(() -> client.changeMemoryMode(true));
+		if (client.getGameState() == GameState.LOGGED_IN)
+		{
+			clientThread.invoke(() -> client.changeMemoryMode(true));
+		}
 	}
 
 	@Override
@@ -55,4 +61,16 @@ public class LowMemoryPlugin extends Plugin
 	{
 		clientThread.invoke(() -> client.changeMemoryMode(false));
 	}
+
+	@Subscribe
+	public void onGameStateChanged(GameStateChanged event)
+	{
+		// When the client starts it initializes the texture size based on the memory mode setting.
+		// Don't set low memory before the login screen is ready to prevent loading the low detail textures,
+		// which breaks the gpu plugin due to it requiring the 128x128px textures
+		if (event.getGameState() == GameState.LOGIN_SCREEN)
+		{
+			client.changeMemoryMode(true);
+		}
+	}
 }