diff --git a/runelite-client/src/main/java/net/runelite/client/game/npcoverlay/NpcOverlayService.java b/runelite-client/src/main/java/net/runelite/client/game/npcoverlay/NpcOverlayService.java
index 242854a4ca..db96bc91a5 100644
--- a/runelite-client/src/main/java/net/runelite/client/game/npcoverlay/NpcOverlayService.java
+++ b/runelite-client/src/main/java/net/runelite/client/game/npcoverlay/NpcOverlayService.java
@@ -33,7 +33,9 @@ import java.util.function.Function;
 import javax.inject.Inject;
 import javax.inject.Singleton;
 import net.runelite.api.Client;
+import net.runelite.api.GameState;
 import net.runelite.api.NPC;
+import net.runelite.api.events.GameStateChanged;
 import net.runelite.api.events.NpcChanged;
 import net.runelite.api.events.NpcDespawned;
 import net.runelite.api.events.NpcSpawned;
@@ -62,6 +64,16 @@ public class NpcOverlayService
 		eventBus.register(this);
 	}
 
+	@Subscribe
+	private void onGameStateChanged(GameStateChanged event)
+	{
+		if (event.getGameState() == GameState.LOGIN_SCREEN ||
+			event.getGameState() == GameState.HOPPING)
+		{
+			highlightedNpcs.clear();
+		}
+	}
+
 	@Subscribe(
 		// Run after plugins, which typically capture NPCs on spawn and reference them in the highlight functions
 		priority = -1